MACE Medication Aide

Category - MACE

You are assisting a patient with their cholesterol medication.  Which of the following drugs reduces LDL cholesterol by inhibiting an intestinal transport protein?

  1. Atorvastatin
  2. Cholestyramine
  3. Ezetimibe
  4. Gemfibrozil
Explanation

Answer − C − The drug that reduces LDL cholesterol by inhibiting an intestinal transport protein is ezetimibe. It is an important newer drug that inhibits cholesterol and bile acid absorption from the gut by inhibiting the epithelial transport protein NPC1L1.

Ezetimibe is a medication used to lower high levels of cholesterol and triglycerides in the blood. It works by blocking the absorption of cholesterol from the small intestine, thereby reducing the amount of cholesterol that enters the bloodstream.

Ezetimibe is usually taken orally in tablet form, either alone or in combination with other cholesterol-lowering medications. The usual recommended dose is 10 mg once daily, with or without food.

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