MACE Medication Aide

Category - CMC

Which of the following pharmacologic agents is not used to treat inflammation?
  1. Nonsteroidal anti-inflammatory drugs
  2. Corticosteroids
  3. Methotrexate
  4. Atorvastatin
Explanation
Answer- D - Atorvastatin is not used to treat inflammation. Pharmacologic agents used ito treat inflammation include analgesics, nonsteroidal anti-inflammatory agents, corticosteroids, anti-malarial agents such as hydroxychloroquine and other agents including methotrexate, sulfoalanine, leflunomide, anti-tumor necrosis factor medications, cyclophosphamide and mycophenolate.

According to the US NIH,  atorvastatin is used together with diet, weight loss, and exercise to reduce the risk of heart attack and stroke and to decrease the chance that heart surgery will be needed in people who have heart disease or who are at risk of developing heart disease. Atorvastatin is also used to decrease the quantity of fatty substances such as low-density lipoprotein (LDL) cholesterol ('bad cholesterol') and triglycerides in the blood and to increase the amount of high-density lipoprotein (HDL) cholesterol ('good cholesterol') in the blood. Atorvastatin may also be used to decrease the amount of cholesterol and other fatty substances in the blood in children and teenagers 10 to 17 years of age who have familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally). Atorvastatin is in a class of medications called HMG-CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body.

Accumulation of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lowering your blood level of cholesterol and fats with atorvastatin has been shown to prevent heart disease, angina (chest pain), strokes, and heart attacks. 

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