Which of the following is the drug of choice for Torsades de Pointes?
  1. Magnesium 1 to 2 g mixed in 50- 100 ml D5W
  2. Atenolol 5mg slow IV
  3. Amiodarone 150 mg IV bolus over 10 minutes
  4. Atropine 0.5 to 1 mg IV
Explanation
Answer- A - The drug of choice for Torsades de Pointes is magnesium 1 to 2 g mixed in 50-100 ml D5W. The ECG reading in Torsades demonstrates a rapid, polymorphic ventricular tachycardia with a characteristic twist of QRS complex around the isoelectric baseline. Treatment is directed at withdrawal of the offending agent, infusion of magnesium sulfate and electrical therapy as needed.
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