Practice Quiz

HT Histotechnician

Category - Fixation

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Which of the following is the advantage of glutaraldehyde over formaldehyde as a fixative?
  1. It is cheap and readily available.
  2. It produces less tissue shrinkage.
  3. It is compatible with many stains.
  4. All of the above.
Explanation
Answer: B - It produces less tissue shrinkage.
The advantage of glutaraldehyde over formaldehyde is that it produces less tissue shrinkage. This is because one of the disadvantages of formaldehyde is it causes significant tissue shrinkage. Moreover, glutaraldehyde is more expensive than formaldehyde and it is not readily available because it needs to be prepared. Formaldehyde is also the fixative widely used because of its compatibility with most stains.
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