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Registered Dietitian

Category - Nutrition Care

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The mechanism by which intestinal mucosa are damaged in celiac sprue involves which of the following? (Choose all that apply.)

Immunologic response to gliadin mediated by T lymphocytes
The breakdown of gliadin into methionine and free fatty acids
Binding of gliadin to receptor sites on the mucosal cell wall
None of the above

Explanation

Answers: A and C - The mechanism by which intestinal mucosa are damaged in celiac sprue involves an immunologic response to gliadin that is mediated by T lymphocytes, after gliadin binds to receptor sites on the mucosal cell wall. This reaction releases chemicals known as lymphokines which damage the cells. Gliadin does not contain either methionine or free fatty acids.

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Registered Dietitian

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