Practice Quiz

CMC Cardiac Medicine Certification

Category - CMC

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The fibrinolytic mechanism of streptokinase and urokinase are:
  1. Inhibit the formation of fibrin by disrupting the conversion of plasminogen to plasmin and activate the conversion of fibrin-bound plasminogen to plasmin respectively
  2. Both inhibit the formation of fibrin by disrupting the conversion of plasminogen to plasmin
  3. Both activate the conversion of fibrin-bound plasminogen to plasmin
  4. Both act directly on fibrin to dissolve it
Explanation
Answer- B - Both inhibit the formation of fibrin by disrupting the conversion of plasminogen to plasmin. Specifically, streptokinase, urokinase, and anistreplase inhibit the formation of fibrin by disrupting the conversion of plasminogen to plasmin. Alteplase, tenecteplase, and reteplase activate the conversion of fibrin-bound plasminogen to plasmin.
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