A 23-year-old woman is complaining of colicky pain in the right lower abdomen after meals and continuous diarrhea. Stools are liquid or semi-formed, with mucus and pus, but without blood. Physical assessment findings include tenderness and mass in the right lower quadrant of the abdomen. The patient is suspected to have Crohn's disease. Which of the following laboratory and diagnostic findings would support the diagnosis?

  1. A cobblestone appearance is recognized on the mucosa of the affected bowel
  2. The mucosa and submucosa of the large intestine is affected
  3. The distribution of the lesions is continuous
  4. Normal levels of folic acid and vitamins A, B complex, and C are detected
Explanation

Answer - A - Crohn's disease affects the entire bowel wall and can involve any portion of the gastrointestinal tract, from the mouth to the anus. The lumen of the affected bowel has a cobblestone appearance; intact tissues are surrounded by fissures and ulcers. Vitamin deficiencies are common because of malabsorption.

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