During the nineteenth century, scientists recognized that cholera and typhoid were spread through contaminated water supplies. By the early part of the twentieth century, major urban areas in Europe and the United States were almost free of these diseases primarily as a result of the development of:
  1. Diagnostic techniques for rapidly identifying infected individuals.
  2. Public-health initiatives focused on sanitizing drinking water and managing sewage.
  3. Broad-spectrum antibiotics capable of curing infected individuals.
  4. Groundwater resources that replaced rivers as the major source of drinking water.
Explanation
Correct Response: B. Cholera and typhoid (or typhoid fever) are both bacterial diseases that spread primarily through food or drinking water contaminated by the wastes of those who have the disease. Improvements in sanitation have nearly eradicated these diseases in the developed world. The ability to diagnose these diseases rapidly (A) was not a major factor in preventing their spread. Broad-spectrum antibiotics (C) were not used until the mid- to late twentieth century. Groundwater resources (D) such as wells were also frequently contaminated by poor sewage management practices and contributed to the spread of cholera and typhoid prior to improvements in sanitation.
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