NCLEX-RN

Category - Pharmacological

Which of the following medications is administered through the oral route for a client with thrombus formation?
  1. Vitamin K
  2. Protamine sulfate
  3. Heparin sulfate
  4. Warfarin (Coumadin)
Explanation
Answer: D - Warfarin is an anticoagulant that works by reducing the liver’s ability to use vitamin K, which is necessary for the activation of clotting factors II, VII, IX and X. Vitamin K partly counteracts warfarin effects; therefore, consumption of foods rich in vitamin K should be avoided during warfarin therapy. Heparin is another anticoagulant, but this medication is administered parenterally. Vitamin K is the antidote for warfarin, whereas protamine sulfate is the antidote for heparin sulfate.
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