NAEP Science Grade 12

Category - Biology

Which of the following best describes an operator in prokaryotic gene expression?
  1. It is a specific nucleotide sequence that indicates where DNA replication begins.
  2. It controls access of RNA polymerase to the genes in a transcription unit.
  3. It is a transposable genetic element that activates an operon.
Explanation
Correct Response: D. An operator is a DNA sequence to which a repressor can bind, blocking RNA polymerase from transcribing prokaryotic genes. The operator does not function as an origin of replication (A), nor is an operator able to remove introns, which are non-coding sections of RNA (B). This process is typically performed by a spliceosome. Transposable elements are segments of DNA that are capable of excising and reinserting themselves into new locations within the chromosome (C). They do not activate operons.
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