HT Histotechnician

Category - Staining

What do you call this stain that is associated with Tay-Sach’s disease?
  1. Modified PAS
  2. Nile blue
  3. Toluidine blue
  4. Borohydride-periodic-schiff
Explanation
Answer: A - Modified PAS
The stain that is associated with Tay-Sach’s disease is modified PAS. In Tay-Sach’s disease, ganglioside is present in storage. To stain gangliosides, modified PAS is used to demonstrate gangliosides within the neurons. All the other choices are not used to demonstrate gangliosides, which are associated with Tay-Sach’s disease.
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