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HT Histotechnician

Category - Fixation

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John Daniel knows that concentrated solutions of formaldehyde must never be neutralized as this will:

Cause increased bleaching of the tissues
Increase the rate of decomposition of formaldehyde
Stimulate violent chemical explosions
Cause formalin to become ineffective as a fixative

Explanation

Answer: C - Stimulate violent chemical explosions
It is a known precaution that formaldehyde should never be neutralized as this action will cause violent chemical explosions in the laboratory. All the other options are not accurate about the reaction of concentrated formaldehyde if it is attempted to be buffered or neutralized.

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