A client with a left-sided heart failure is prescribed with digoxin (Lanoxin) and furosemide (Lasix). Which of the following signs and symptoms alerts the nurse for a possible occurrence of digoxin toxicity?
  1. A positive Trousseau's sign
  2. Leg cramps
  3. Diarrhea
  4. Muscle twitching
Answer - B - Hypokalemia increases the client's risk for digoxin toxicity. Hypokalemia is manifested by absent leg cramps and muscle weakness. Option A and D indicate hypocalcemia. Option C indicates hyperkalemia.
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