NCLEX-RN

Category - Physiological

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A 69-year-old man is admitted in the hospital for influenza. The medical history reveals Alzheimer’s disease, diagnosed two years ago. Alzheimer’s disease is caused by biochemical and neuropathological changes characterized specifically by all of these, except:

Tangled masses of neurons
Increased acetylcholine
Formation of neuritic plaques
Decreased brain size

Explanation

Answer: B - Alzheimer’s disease is characterized by decreased acetylcholine in the brain. This neurotransmitter is involved in memory processing. The presence of neurofibrillary tangles of neurons and neuritic (senile) plaques in the brain are characteristic of Alzheimer’s disease. This neuronal damage results in decreased brain size.

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