A 45 year old male patient presented to the emergency room with crushing chest pain. Although his EKG did not show ST-elevation, he did have a Troponin I level of 4.0. The emergency room physician has ordered Eptifibatide Bolus. What serum levels are important to monitor when on Eptifibatide?
  1. INR ,PTT, and Platelets
  2. Hemoglobin and Hematocrit
  3. INR only
  4. INR,PTT,Platelets,Hemoglobin,Hematocrit and Creatinine
Explanation
Answer: D - In patients who have been administered Eptifibatide, a GP IIb-IIIa inhibitor, serum levels of INR, PTT, Platelets, Hemoglobin, Hematocrit and Creatinine should all be monitored post bolus. Eptifibatide is indicated for use in non ST-elevation (NSTEMI) and can cause severe bleeding along with renal impairment so it is vital to monitor for this.
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