Answer − A− The drug that is the treatment of choice for Candida albicans infection is fluconazole. Fluconazole is an antifungal that prevents the fungal enzyme Cytochrome P450 from working. In addition, itraconazole is also considered a drug of choice for systemic Candida albicans infection.
Candida albicans is a type of yeast commonly found in the human body. It is a normal part of the gut flora and is usually harmless. However, when the balance of bacteria in the body is disrupted, Candida albicans can overgrow and cause an infection. This is known as a Candida infection, or candidiasis.
Candida infections can affect various body parts, including the mouth, throat, esophagus, and genital area. The symptoms of a Candida infection can vary depending on the location of the infection but may include itching, burning, soreness, and redness. In severe cases, a Candida infection can spread to the bloodstream and cause serious health problems.
Candida infections are more common in people with weakened immune systems, such as those with HIV/AIDS, and in people who have taken antibiotics for an extended period of time. Treatment for a Candida infection typically involves antifungal medication, which can be taken orally or applied topically, depending on the location and severity of the infection.
Fluconazole is an antifungal medication that is used to treat infections caused by the yeast Candida. It works by disrupting the formation of the fungal cell wall, which is essential for the survival of Candida. The drug binds to a specific protein in the cell wall called ergosterol, a component of the fungal cell membrane. By binding to ergosterol, fluconazole interferes with the normal function of the cell wall, leading to the death of the Candida cells.
In addition to its direct effects on Candida cells, fluconazole can also affect other components of the fungal cell, such as enzymes and transporters, which are involved in the growth and survival of the yeast. By inhibiting these cellular functions, fluconazole helps to stop the spread of Candida and reduce the overall population of the yeast, leading to the resolution of the infection.
