Adult Nurse Practitioner Exam Prep

Answer - A - Unlike Central Diabetes Insipidus, Nephrogenic diabetes insipidus is caused by the kidney’s resistance to ADH rather than a deficiency of this hormone. This results in a decreased ability of the kidneys to concentrate the urine. The disease is rare, but 90% of the known cases are believed to be X-linked, which causes the vasopressing receptor to not function properly. The primary symptom of NDI is excessive thirst and excretion of large amount of urine. Dehydration is a common complication of the disease.