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Which of the following is most characteristic of the brain in patients with Alzheimer’s disease?
  1. Neuronal loss in the cerebral cortex
  2. Demyelination in the cerebral cortex
  3. Posterior column degeneration
  4. Neuronal loss in the cerebellar cortex
Explanation
Answer: A - The most prominent characteristics of Alzheimer’s disease are neuronal loss, fibrillary tangles, loss of synapses, and amyloid (or neuritic) plaque formation.
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