INBDE Integrated National Board Dental Exam Prep Set 2

Answer: B - Nikolsky's sign is the rubbing of uninvolved mucosa resulting in a blister. This is a sign and symptom of penphigus vulgaris. Additional signs and symptoms include oral lesions that appear before skin involvement, tzanck cells, and intraepithelial cleft formation. The condition is rare, but usually seen in adults and has equal distribution among genders. It can be fatal if left untreated with aggressive steroid therapy and immunosuppressive drugs.