What syndrome displays freckle-like spots on the hands, oral mucosa, and perioral skin?
  1. Nerve compression syndrome
  2. Saal Bulas syndrome
  3. CREST syndrome
  4. Peutz-Jeghers syndrome
Explanation
Answer: D - Peutz-Jeghers syndrome displays freckle-like spots on the hands, oral mucosa, and perioral skin. The freckle-like spots are not considered cancerous, but there is an association with intestinal polyposis, GI adenomas, ovarian, pancreatic, and breast carcinoma. The spots are usually small blue-gray macules in the vermillion zone, buccal mucosa, tongue, mouth, nose, anus, genital areas, and vermillion zone.
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