Which of the following statements is not true of total peripheral resistance (TPR)?
  1. it is influenced by sympathetic activation
  2. it is directly proportional to cardiac output
  3. it is directly proportional to mean arterial pressure
  4. it is influenced by thermal changes
Explanation
Answer: B - TPR is the vascular resistance of the systemic circulation. Thus, TPR is indirectly proportional to cardiac output.
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