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INBDE Integrated National Board Dental Exam Prep

Category - INBDE

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The rate-limiting step in glycolysis occurs at the step catalyzed by which of the following enzymes?

glyceraldehyde-3-phosphate dehydrogenase
6-phosphofructo-1 kinase, PFK-1
6-PFK-2
phosphoglycerate kinase
pyruvate kinase

Explanation

Answer: B - The primary site of regulation of glycolysis occurs at the level of the PFK-1 catalyzed step. Hence, this reaction is the rate-limiting step in glycolysis.

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