USMLE Exam Prep

Answer - C - Sickle-cell anemia can be diagnosed using a blood smear because of the characteristic “sickle” shape of the red blood cells. The other forms of anemia would require additional tests, as they would interfere with appropriate red blood cell production. Although there might be some morphological changes noted, these forms do not have the clear morphological distinctions that sickle-cell anemia has.