The herbal remedy St John’s Wort may interact with which of the following medications?
  1. Statin drugs
  2. Digoxin
  3. Coumadin
  4. All of the above
Explanation
Answer: D - The herbal remedy St John’s Wort, used to treat mild to moderate depression, may have adverse reactions with statin drugs, digoxin, and coumadin. It may decrease the effectiveness of all of these medications by interfering with the biochemical pathways by which they are metabolized.
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