Podiatry and Medical - Set 1

Category - Podiatry Part I

Which of the following is the most common side effect of colchicine?
  1. Cardiac side effects
  2. Gastrointestinal side effects
  3. Hepatic side effects
  4. Pulmonary side effects
Explanation
Answer − B − The most common side effect of colchicine is gastrointestinal side effects, namely nausea, vomiting, and diarrhea. Colchicine acts by inhibiting microtubule polymerization by binding to tubulin, one of the main constituents of microtubules. This is the main advantage of celecoxib over other nonsteroidal anti-inflammatory (NSAIDs) medications.
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