Answer: B. prevacuum steam sterilizer
The best method of terminal sterilization, particularly for healthcare settings and for sterilizing a wide range of medical devices and instruments, is often considered to be the prevacuum steam sterilizer. This method utilizes steam under pressure with a prevacuum phase to remove air from the sterilization chamber, allowing for faster and more effective penetration of steam into the items being sterilized. Prevacuum steam sterilization is efficient, effective against a wide range of microorganisms including spores, and is suitable for most medical instruments and materials that can withstand heat and moisture.