Practice Quiz

Registered Dietitian

Category - Nutrition Science

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Which of the following is NOT true of a randomized, double-blind clinical research trial?
  1. Participants in the treatment group are carefully matched to control subjects.
  2. Both the study investigators and participants are unaware of which subjects are receiving treatment or intervention.
  3. Placebo treatments are never used.
  4. Participants are divided into treatment/control groups without bias.
Explanation
Answer: C - The statement which is not true of randomized, double-blind clinical research trials is that placebo treatments are never used. Placebo treatments are used frequently in clinical trials to measure the effects of real treatment versus effects of inactive substances on a disease or health condition. In a double-blind research trial, neither investigators nor study participants know which subjects are receiving treatment. In addition, study subjects are carefully matched by age, sex, health status, etc., to similar control subjects, and both study subjects and controls are randomly assigned to avoid study bias.
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