MACE Medication Aide

Category - MACE

Which of the following is considered the “drug of choice” for Clostridium difficile?
  1. Metronidazole
  2. Clindamycin
  3. Ketoconazole
  4. Ciprofloxacin
Explanation
Answer: A - Metronidazole is the drug of choice against Clostridium difficile due to its lower price and good clinical efficacy. Clindamycin is ineffective against Clostridia, and Clostridia overgrowth is a serious potential adverse effect. Ketonidazole is an azole antifungal. Ciprofloxacin is fluroquinone without high efficacy against Clostridium difficile.
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