MACE Medication Aide

Category - MACE

Which of the following has a “black box warning” associated with it?

I. Celecoxib
II. Ibuprofen
III. ACE inhibitors
IV. Acarbose
  1. I only
  2. I and II only
  3. I, II and III only
  4. All of the above
Explanation
Answer: C - Celecoxib/Celebrex, a COX-2 inhibitor, carries the increased risk of thrombotic, GI and cardiac events. Ibuprofen, an NSAID also carries the increased risk of thrombotic, GI and cardiac events. ACE inhibitors, as a class, can cause injury and death to a developing fetus. Acarbose is a hypoglycemic and carries no black box warning.
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