Which of the following explanations best describes the mechanism of hepatic encephalopathy?
  1. Increased level of uric acid in the blood
  2. Increase level of viral agents in the blood
  3. Increased level of bacteria in the blood
  4. Increased level of ammonia in the blood which crosses blood brain barrier and is absorbed in blood cells.
Explanation
Answer: D - Increased level of ammonia in the blood which crosses blood brain barrier and is absorbed in blood cells best describes the mechanism of hepatic encephalopathy. Hepatic failure is a state in which the liver is no longer be able to perform normal function due to different factors. Hepato-renal syndrome and Hepatic encephalopathy are the parts of syndrome of hepatic failure. An increased level of ammonia is responsible for an altered level of consciousness, stupor or coma in hepatic encephalopathy.
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