Practice Quiz

Podiatry and Medical - Set 1

Category - Podiatry Part I

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Which of the following drugs is selectively antifungal because of the difference between cholesterol (in mammalian cell membranes) and ergosterol (in fungal membranes)?
  1. Amphotericin B
  2. Caspofungin
  3. Fluconazole
  4. Griseofulvin
Explanation
Answer − A − The drug that is selectively antifungal because of the difference between cholesterol (in mammalian cell membranes) and ergosterol (in fungal membranes) is amphotericin B. Amphotericin B binds selectively to ergosterol and forms artificial pores in fungal membranes.
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