Podiatry and Medical - Set 1

Category - Podiatry Part I

Which of the following enzymes is inhibited by drugs of the class to which amoxicillin belongs?
  1. Alanine racemase
  2. Beta lactamase
  3. Enolpyruvate transferase
  4. Transpeptidase
Explanation
Answer − D − The enzyme that is inhibited by drugs of the class to which amoxicillin belongs is transpeptidase. All of the beta-lactam antibiotics (penicillins, cephalosporins, carbapenems, monobactams) inhibit one of the final steps in the synthesis of the bacterial cell wall, cross-linking of peptidoglycan chains by transpeptidase
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