MACE Medication Aide

Category - MACE

Which of the following drugs is contraindicated for a 28-year-old female taking oral contraceptives?

I. Macrolides
II. Rotinavir
III. Barbiturates
  1. I only
  2. II only
  3. III only
  4. All of the above
Explanation
Answer: D - The macrolides, barbiturates and rotinavir all have known interactions with oral contraceptives, interfering with Phase I and Phase II reactions. Macrolides, anti-retrovirals and barbiturates are all associated with decreased oral contraceptive efficacy.
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