MACE Medication Aide

Category - MACE

Which of the following drugs are CYP2D6 inhibitors?

I. Amiodorone/Cirdarone
II. Imatamib/Gleevec
III. Thioridazine/Mellaril
IV. Terbinafine/Lamisil
  1. I and II only
  2. I, II and III only
  3. II only
  4. All of the above
Explanation
Answer: D - All the drugs listed are inhibitors of the CYP2D6 pathway and can interact with other medications to produce serious adverse effects by increasing the serum concentrations of drugs metabolized by the CYP2D6 pathway.
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