Practice Quiz

FPGEE Foreign Pharmacy

Category - Pharmaceutical

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Which of the following classes of medications should not be taken with St John’s wort?

I. MAOI inhibitors
II. SSRIs
III. Hormonal contraceptives
IV. Vinca alkaloids
  1. I and II only
  2. I, II and III only
  3. I and III only
  4. All of the above
Explanation
Answer: D - St John’s Wort (Hypericum perforatum) has been shown to have interactions with all the listed classes. Its mechanism of action makes it essentially an MAOI inhibitor and an SSRI (Selective Serotonin Reuptake Inhibitor).
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