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MACE Medication Aide

Category - MACE

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Which of the following are possible adverse effects of methotrexate?

I. Leukoencephalopathy
II. Tubular necrosis
III. Hepatotoxicity
IV. GI bleed

I and II only
II and III only
I and III only
All of the above are possible adverse effects.

Explanation

Answer: D - Methotrexate is a folic acid antagonist used as an immunosuppressant and an antineoplastic agent. All of the listed adverse effects are possible with methotrexate use.

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