MACE Medication Aide

Category - MACE

Which of the following are common anti-emetics used as adjuncts in chemotherapy?

I. Aprepitant
II. Ondansetron
III. Metoclopramide
IV. Palonosetron.
  1. I and III only
  2. II and IV only
  3. II and III only
  4. All are anti-emetics
Explanation
Answer: D - All of the listed drugs are used as anti-emetics in oncology. Aprepitant (Emend) is a neurokinin-1 antagonist. Ondansetron (Zofran) and Palonosetron (Aloxi) are 5HT3 receptor antagonists. Metoclopramide (Reglan, Metazol, Octamide) is a dopamine-2 antagonist.
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