FPGEE Foreign Pharmacy

Category - Pharmaceutical

For the following chemotherapeutic agents, determine the incorrect combination of agent/mechanism of action.

I. Cyclophosphamide/alkylating agent
II. Paclitaxel/anti-mitotic
III. Leuprolide/Leukocyte antagonist
IV. Doxorubicin/alkylating agent
  1. I and II only.
  2. II and IV only.
  3. III and IV only.
  4. I and III only.
Explanation
Answer: C - In choice I and II, the drugs are correctly paired with the mechanism of action. Leuprolide is a Gonadotropin-releasing Hormone (GnRH) analog/antagonist. Doxorubicin is an anthracycline derivative and inhibits DNA/RNA synthesis by intercalation.
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