MACE Medication Aide

Category - MACE

A patient has an implanted coronary stent, and ticlopidine has been prescribed. Which of the following choices best complete the statement:
Ticlopidine is a(n) ___________. Major adverse reactions involve ___________ and ___________. ___________ should NOT be taken concurrently with ticlopidine.
  1. Glycoprotein-receptor inhibitor, spinal hemorrhage, pulmonary hemorrhage, warfarin
  2. Platelet aggregation inhibitor, bleeding, bone marrow depression, aspirin
  3. Anti-coagulant, hemorrhage, hepatitis, hormonal contraceptives
  4. Vitamin-K inhibitor, uncontrolled bleeding, fever, aspirin
Explanation
Answer: B - Ticlopidine (Ticlid) is a platelet aggregation inhibitor. GI and intracerebral hemorrhages and bone marrow depression are serious adverse reactions. Other adverse reactions include blood dyscrasias. Statement A is true of tirofian (Aggrastat), another platelet aggreagation inhibitor. Statements C and D are true of warfarin (Coumadin), a classic anticoagulant.
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