Practice Quiz

MACE Medication Aide

Category - MACE

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A patient diagnosed with PCOS (polycystic ovarian syndrome) is prescribed spironolactone along with a combined estrogen-progestin. What would you tell her about the serious possible side effects of the spironolactone?
  1. The serious possible side effects include breast discomfort and increased urinary frequency.
  2. The serious possible side effects include breast discomfort and increased appetite.
  3. The serious possible side effects include GI bleeds, breast cancer, metaolic acidosis and hyperkalemia.
  4. The serious possible side effects include breast discomfort and increased breast size.
Explanation
Answer: C - Spironolactone, an aldosterone inhibitor and therefore a diuretic (K+ sparing), has been associated with GI bleeds, breast cancer, metaolic acidosis and hyperkalemia. The other side effects listed are primarily associated with the use of the combined estrogen-progestin.
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