A hypertensive patient comes for routine follow up. His EKG demonstrates a PR interval of 220 milliseconds. Which of the following drugs is most likely culprit for this EKG finding?
  1. Simvastatin
  2. Nifedipine
  3. Hydrochlorothiazide
  4. Sorbitrate
Explanation
Answer- B - The most likely culprit for this EKG finding is nifedipine. Pharmacologic agents that can lead to first-degree atrioventricular block include digoxin, calcium channel blockers such as nifedipine, amlodipine, verapamil, diltiazem and beta-blockers.
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