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Ophthalmic Technician

Category - Ophthalmic Imaging

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A 45-year-old male with proliferative diabetic retinopathy is advised to undergo fundus fluorescein angiography. The fundus images, taken prior to injection of fluorescein dye, reveal fluorescence at the optic nerve head. What is this phenomenon called?

Hyperfluorescence
Hypofluorescence
Pseudofluorescence
Autofluorescence

Explanation

Answer: D - Autofluorescence is the appearance of fluorescence before injecting the fluorescein dye.

Autofluorescence is seen in optic nerve head drusen and is due to the presence of lipofuscin, which is autofluorescent.

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