CRNE Exam Prep

Category - Changes in Health

A male client with alcohol dependence will be placed on disulfiram therapy. Before the start of the therapy, the nurse reminds the client that disulfiram is an alcohol deterrent, which will sensitize the client to alcohol. The nurse instructs the client to abstain from alcohol for at least:
  1. 72 hours
  2. 48 hours
  3. 24 hours
  4. 12 hours
Explanation
Answer: D - The nurse instructs the client to abstain from alcohol for at least 12 hours before the initial dose. Adverse effects of disulfiram therapy include facial flushing, sweating, and respiratory distress. The client must also avoid drinking alcohol for at least 14 days after quitting the therapy, as disulfiram-alcohol interaction may still occur within this time period.
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