MACE Medication Assistant Exam Prep

Category - Medication Assistant

What class of drugs is recommended as the first line therapy for hypercholesterolemia, after lifestyle modifications?
  1. HMG CoA reductase inhibitors (statins)
  2. Calcium channel blockers
  3. Beta channel antagonists
  4. Antithrombolytics
Explanation
Answer: A - The statins work by blocking an enzyme, HMG-CoA reductase that is the rate-limiting step in the manufacture of cholesterol. Statins reduce LDL-cholesterol, total cholesterol, and triglycerides and slightly increase high-density lipoprotein (HDL-c).
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