Podiatry and Medical - Set 1

Category - Podiatry Part I

Which one of the following anti-inflammatory drugs used in rheumatoid arthritis has a mechanism of action that leads to a decrease in tumor necrosis factor?
  1. Etanercept
  2. Sulfasalazine
  3. Prednisone
  4. Rofecoxib
Explanation
Answer − A − An anti-inflammatory drug that is used in rheumatoid arthritis and has a mechanism of action that leads to a decrease in tumor necrosis factor (TNF) is etanercept. Etanercept binds to TNF, resulting in the inactivation of this powerful cytokine, which plays a major role in a number of inflammatory disorders including Crohn’s disease and rheumatoid arthritis.
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