Podiatry and Medical - Set 1

Category - Podiatry Part I

Which of the following statements best describes the mechanism of action of oral anticoagulants such as warfarin?
  1. Break down thrombin
  2. Form an active complex with
  3. Plasminogen
  4. Inhibit hepatic carboxylation of coagulation factor precursors
Explanation
Answer − D − The statement that best describes the mechanism of action of oral anticoagulants such as warfarin is: “inhibit hepatic carboxylation of coagulation factor precursors.” The oral anticoagulants such as warfarin block the vitamin K-dependent step in the hepatic synthesis of coagulation factors VII, IX, X, and prothrombin.
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