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Podiatry and Medical - Set 1

Category - Podiatry Part I

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Which of the following statements associates the correct mechanism of action with a drug used in Type II (noninsulin-dependent) diabetes?

Acarbose-reduction of insulin resistance
Glipizide-inhibition of intestinal alphaglucosidase
Metformin-inhibition of atp-sensitive potassium channels
Repaglinide-modulation of pancreatic insulin release

Explanation

Answer − D − The statement that associates the correct mechanism of action with a drug used in Type II (noninsulin-dependent) diabetes is: repaglinide-modulation of pancreatic insulin release. Modulation of insulin release is the mechanism of action of the meglitinides such as repaglinide. These drugs share one binding site with sulfonylureas and have a second, independent binding site.

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Podiatry and Medical - Set 1

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Podiatry and Medical - Set 1

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