MACE Medication Assistant Exam Prep

Category - Pharmacological

Which of the following drugs are vitamin K antagonists?

  1. Immunosuppresants
  2. Antidepressants
  3. Thiazide diuretics
  4. Anticoagulants
  5. All of the above
  6. None of the above
Explanation

Answer: D - Anticoagulants are vitamin K antagonists. Vitamin K is involved in the regulation of blood clotting. Because they prevent blood clotting, anticoagulants oppose the action of vitamin K. This isn't a bad thing.  Rather it's the action of the anti-coagulant drugs.  For example, the metabolism of warfarin (Coumadin), vitamin K, and vitamin K dependent clotting factors occurs in liver.   Warfarin (Coumadin) prevents the production of vitamin K-dependent clotting factors.  As a result, clotting occurs at a much slower rate.  

Source: National Blood Clot Alliance

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