Practice Quiz

PTA Physical Therapy Assistant

Category - Diseases and Conditions

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Which factor is responsible for ankylosing spondylitis?
  1. IgM
  2. HLA- B27
  3. Both A. and B.
Explanation
Answer: B -HLA - B27 factor is responsible for ankylosing spondylitis.

Ankylosing spondylitis is a chronic, progressive, crippling disease affecting the spine. There should be a strong genetic association for this condition. Commonly HLA - B27 factors are more prone for contracting the disease. In lab testing, this factor will be positive.

IgM is a rheumatic factor which is positive in rheumatoid arthritis.
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