The non-insulin-dependent diabetic who is obese is best controlled by weight loss because obesity:
  1. Reduces the number of insulin receptors
  2. Causes pancreatic islet cell exhaustion
  3. Reduces insulin binding at receptor sites
  4. Reduces pancreatic insulin production
Explanation
Answer - C - Obesity causes a reduce insulin binding at receptor sites and this leads to pancreatic hypersecretion of insulin and eventual pancreatic cell exhaustion.
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